Airway smooth muscle (ASM) lies at the core of bronchomotor tone and undergoes profound alterations in chronic airway diseases. In asthma and chronic obstructive pulmonary disease (COPD), ASM exhibits ...

The natriuretic peptides, specifically brain natriuretic peptide (BNP), are the most specific and applicable laboratory tests available to establish fluid overload associated with HF. 9 BNP is ...

Chronic obstructive pulmonary disease (COPD) is a group of diseases that affect the lungs. The disease makes it difficult to breath and progressively gets worse. About 15 million Americans have been ...

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease—the fourth leading cause of ...

Elevated sputum azurocidin-1 levels correlate with worsening lung function and increased exacerbation frequency in patients with bronchiectasis.

Why is it that we have not seen the urgency in COPD management we would expect for a disease of this burden and scale? As a trained pulmonologist, and having dedicated my career to advancing ...

Panelists discuss how the pathophysiology of pulmonary arterial hypertension involves complex mechanisms across multiple genetic and treatment pathways, with over 20 identified genes and four major ...

Chronic obstructive pulmonary disease, or COPD, is among the most common lung diseases in the world. COPD is a blanket term for several progressive lung diseases such as emphysema, chronic bronchitis, ...

A doctor and patient both offer their perspectives on the challenges of returning home from the hospital after a COPD exacerbation.

Pulmonary hypertension (PH) is characterised by pathological elevation of pressure in the pulmonary circulation, driven by endothelial dysfunction, smooth muscle proliferation and inflammatory ...

Asthma and chronic obstructive pulmonary disease (COPD) are chronic respiratory diseases that cause breathing difficulty and coughing. Both conditions share similar symptoms. Understanding their ...