In the life sciences, cryogenic electron microscopy (cryo-EM) has revolutionized structure determination by providing atomic-resolution structures of biomolecules in their native environment and in ...

Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

The video opens with Professor Alex Johnson speaking directly to the camera. A lower-third graphic appears with his name and title. It reads, "Alex Johnson Assistant Professor of Biochemistry." Scenes ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open ...

Our understanding of eukaryotic cell function at the fundamental level of molecular structures and interactions remains incomplete. Although individual components can be studied in isolation or in ...

In conjunction with the Structural Biology Core Facility, CEMIL enables practitioners of Cryo-EM within MSK laboratories to design innovative experiments and collect the highest quality Cryo-EM data ...

Cryo-correlative light and electron microscopy (cryo-CLEM) is a powerful technique that combines fluorescence imaging for specific localization with electron microscopy for detailed structural ...

Berkeley Lab and UC Berkeley physicists' new technique offers detailed images of the small molecules and cell structures that ...

In this issue of BioTechniques, we present a method for Mycobacterium tuberculosis detection using a colorimetric single-tube nested PCR assay, a strand displacement amplification method for ...

From paints and inks to catalysts and drug-delivery materials, many advanced technologies rely on substances dispersed in ...

Using cryo-electron microscopy, researchers at Case Western Reserve University School of Medicine and National Institutes of Health open door to new level of detail in study of abnormal proteins that ...