Type 2 diabetes (T2D) is associated with β-cell dedifferentiation. Aldehyde dehydrogenase 1 isoform A3 (ALHD1A3) is a marker of β-cell dedifferentiation and correlates with T2D progression. However, ...

A new research perspective titled "Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation" has been published in Oncotarget. "One mode of ...

Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit ...

A new research perspective was published in Oncotarget's Volume 15 on January 24, 2024, entitled, "Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic ...

Figure 1: Representative histopathologic slides stained with hematoxylin and eosin of thyroid cancer from well-differentiated to dedifferentiated states. “One mode of resistance is the transition to ...