Schematic diagram of the IL-6/JAK/STAT3 signaling pathway activation in mouse liver macrophages. IRs, inhibitory receptors (IRs); ICIs, immune checkpoint inhibitors; IL-6, interleukin-6; ALT, alanine ...
Cancer-associated fibroblasts (CAFs) are the dominant component of the tumor microenvironment (TME), which contributes to tumor progression. Aldo-keto reductase 1 family member C3 (AKR1C3) has been ...
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