A team of cryo-engineers and surgeons at the University of Minnesota has found a way to cryogenically freeze and thaw rat organs in a way that preserves their viability. In their study, reported in ...

Thousands of donated organs are discarded every year. As soon as one becomes available, doctors race to find a compatible recipient—but transplantation time lines are measured in hours, and many ...

Kidney transplantation remains the most effective treatment for end-stage kidney disease, yet a severe shortage of donor organs continues to limit access for millions of patients worldwide. With ...

Advanced cancers induce systemic responses. However, if such systemic changes occur already when aggressive tumors are small, have not been thoroughly characterized. Here, we examined how localized ...

Rat kidneys have been successfully grown in mice – offering hope for millions of people waiting for transplants. The ...

Rat embryonic stem cells (red) generate kidney tissue in Osr1-deficient mouse embryos via interspecies blastocyst complementation. The nephron structure and collecting duct (E-cadherin, green) are ...